Monday, February 22, 2010

Acute Myocardial Infarction


Acute MI



Any degree of myocardial necrosis caused by myocardial ischemia and detected using a sensitive and specific preferred biomarker, such as cardiac troponin.

Acute Myocardial Infarction

=Annual incidence in US:  900,000
=Mortality:  225,000
=Pre-admission mortality:  125,000











Congestive Heart Failure

http://www.slideworld.org/slidestag.aspx/physiology

Objectives



Review cardiac physiology and pathophysiology of CHF
Early recognition of CHF
Management of CHF
Use of CPAP

Terminology

Heart Failure: The inability of the heart to maintain an output adequate to maintain the metabolic demands of the body.
Pulmonary Edema: An abnormal accumulation of fluid in the lungs.
CHF with Acute Pulmonary Edema: Pulmonary Edema due to Heart Failure (Cardiogenic Pulmonary Edema)







Stem Cell Therapy: Clinical Results


Stem cell therapy




=are primitive cells
=can renew themselves
=can develop into different cell types
=have the potential to become more differentiated cells

Embryonic stem cells

=derived from the early embryo
=are totipotent (can differentiate into all cell types of all organs)
=used to create gene knockout (KO) animal models for CVD study